Here are some of our latest works.
Tiburcio PDB, Chen K, Xu L, Chen KS. Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor. bioRxiv [Preprint]. June 13, 2024. doi:10.1101/2024.06.11.598518
Schoettler PJ, Smith CC, Nishitani M, Harris AK, Nelson AT, Watson DA, Kamihara J, Mullen EA, Hill DA, Messinger YH, Fair DB, Kumar KA, Dehner LP, Ash S, Chen KS, Schultz KAP. Anaplastic Sarcoma of the Kidney (DICER1-Sarcoma of the Kidney): A Report from the International Pleuropulmonary Blastoma/ DICER1 Registry. Pediatr Blood Cancer. 2024; e31090. doi:10.1002/pbc.31090 | PubMed
Fraire CR, Desai K, Obalapuram UA, Mendyka LK, Rajaram V, Sebastian T, Wang Y, Onel K, Lee J, Chen KS. An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma. bioRxiv [Preprint]. April 25, 2024. doi:10.1101/2024.04.23.590638v3
Tiburcio PDB, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Xu L, Chen KS. DROSHA regulates mesenchymal gene expression in Wilms tumor. Mol Cancer Res. 2024 Apr 22. doi:10.1158/1541-7786.MCR-23-0930 | PubMed
Fraire CR, Mallinger PR, Hatton JN, Kim J, Dickens DS, Argenta PA, Milanovich S, Hartshorne T, Carey DJ, Haley JS, Urban G, Lee J, Hill DA, Stewart DR, Schultz KAP, Chen KS. Intronic germline DICER1 variants in patients with Sertoli-Leydig cell tumor. JCO Precis Oncol. 2023; 7: e2300189. doi:10.1200/PO.23.00189 | PubMed | PMC
Schultz KAP, Chintagumpala M, Piao J, Chen KS, Shah R, Gartrell RD, Christison-Lagay E, Pashnakar F, Berry JL, O'Neill AF, Vasta LM, Flynn A, Mitchell SG, Seynnaeve BKN, Rosenblum J, Potter SL, Kamihara J, Rodriguez-Galindo C, Hawkins DS, Laetsch TW. Rare tumors: Opportunities and challenges from the Children's Oncology Group perspective. EJC Paediatric Oncol. 2023 Dec; 2: 100024. doi:10.1016/j.ejcped.2023.100024 | PubMed | PMC
Schultz KAP, Chintagumpala M, Piao J, Chen KS, Gartrell R, Christison-Lagay E, Berry JL, Shah R, Laetsch TW. Children's Oncology Group's 2023 Blueprint for Research: Rare Tumors. Pediatr Blood Cancer. 2023; e30574. doi:10.1002/pbc.30574.
Aguayo JS, Shelton JM, Tan W, Rakheja D, Cai C, Shalaby A, Lee J, Iannaccone ST, Xu L, Chen KS, Burns DK, Zheng Y. Ectopic PLAG1 induces muscular dystrophy in the mouse. Biochem Biophys Res Commun. 2023 Jul 12;665:159-168. doi:10.1016/j.bbrc.2023.05.006 | PubMed