Zhang L, Mallinger PHR, Zhou S, Makri SC, Gross JM, Lucas CHG, Zou YS, Mize W, Olson DR, Munnikhuysen SR, Rawwas J, Messinger Y, Chen KS, Schultz KAP, Pratilas CA. RAS pathway targeted therapy in patients with DICER1-associated sarcomas. npj Precis Oncol. 2025; 9: 232. doi:10.1038/s41698-025-01026-0  |  PubMed

Tiburcio PDB*, Desai K*, Warne A, Nabbi A, Zhou S, Reiff SD, Campbell ME, Amatruda JF, Chen KS. PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumor. Pediatr Blood Cancer. 2025. doi:10.1002/pbc.31852  |  PubMed  |  bioRxiv

Tiburcio PDB, Chen K, Xu L, Chen KS. Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor. Cell Reports Medicine. 2025. doi:10.1016/j.xcrm.2025.102133  |  PubMed  |  PMC  |  bioRxiv

Fraire CR, Desai K, Jagadeeswaran I, Obalapuram UA, Mendyka LK, Rajaram V, Sebastian T, Wang Y, Onel K, Lee J, Chen KS. An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma. Genes Dev. 2025. doi:10.1101/gad.352485.124  |  PubMed  |  bioRxiv

Schoettler PJ, Smith CC, Nishitani M, Harris AK, Nelson AT, Watson DA, Kamihara J, Mullen EA, Hill DA, Messinger YH, Fair DB, Kumar KA, Dehner LP, Ash S, Chen KS, Schultz KAP. Anaplastic Sarcoma of the Kidney (DICER1-Sarcoma of the Kidney): A Report from the International Pleuropulmonary Blastoma/DICER1 Registry. Pediatr Blood Cancer. 2024; e31090. doi:10.1002/pbc.31090  |  PubMed  |  PMC

Tiburcio PDB, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Xu L, Chen KS. DROSHA regulates mesenchymal gene expression in Wilms tumor. Mol Cancer Res. 2024 Apr 22. doi:10.1158/1541-7786.MCR-23-0930  |  PubMed  |  PMC  |  bioRxiv

Fraire CR, Mallinger PR, Hatton JN, Kim J, Dickens DS, Argenta PA, Milanovich S, Hartshorne T, Carey DJ, Haley JS, Urban G, Lee J, Hill DA, Stewart DR, Schultz KAP, Chen KS. Intronic germline DICER1 variants in patients with Sertoli-Leydig cell tumor. JCO Precis Oncol. 2023; 7: e2300189. doi:10.1200/PO.23.00189  |  PubMed  |  PMC

Aguayo JS, Shelton JM, Tan W, Rakheja D, Cai C, Shalaby A, Lee J, Iannaccone ST, Xu L, Chen KS, Burns DK, Zheng Y. Ectopic PLAG1 induces muscular dystrophy in the mouse. Biochem Biophys Res Commun. 2023 Jul 12;665:159-168. doi:10.1016/j.bbrc.2023.05.006  |  PubMed